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Table 1 Recommended intakes of EPA + DHA by cohort and organization

From: Omega-3 fatty acids for breast cancer prevention and survivorship

Cohort

Source

Daily recommendation

General health

  

 Adults

US Department of Agriculture

≥250 mg

 Adults

European Food Safety Agency

≥250 mg

 Adults

World Health Organization:

≥250 mg

 Adults

Academy of Nutrition and Dietetics

≥500 mg

 Adults without CHD

American Heart Association

500 mg (fatty fish ≥ 2 times/week)

 Adults

International Society for the Study of Fatty Acids and Lipids

≥500 mg

Pregnancy

  

 Pregnant/lactating

International Society for the Study of Fatty Acids and Lipids

≥500 mg (≥300 mg DHA)

 Pregnant/lactating

European Food Safety Agency

≥250 mg (100 to 200 mg DHA)

Heart disease and inflammatory disorders

 

 CHD

American Heart Association

1 g

 Patients with high TG

American Heart Association

2 to 4 g

Generally viewed as safe upper limit

 

 Population

US Food and Drug Administration

≤3 g EPA + DHA

 Population

European Safety Authority

5 g EPA + DHA

  1. CHD, coronary heart disease; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; TG, triglyceride.