Figure 2
From: Long-term hazard of recurrence in HER2+ breast cancer patients untreated with anti-HER2 therapy
Annual hazards and time-dependent hazard ratio for disease recurrence in centrally confirmed HER2+ patients by HR status. (a) Annual hazard of disease recurrence in centrally confirmed HER2+ placebo patients in TEACH, according to HR status (95% confidence limits at 2-year intervals). (HR+ = ER+ and/or PR+; HR- = ER- and PR-). (b) Hazard ratio for disease recurrence in centrally confirmed HER2+ placebo patients in TEACH, comparing HR+ versus HR-. (HR+ = ER+ and/or PR+; HR- = ER- and PR-). ER-, estrogen receptor negative; ER+, estrogen receptor positive; HER2+, human epidermal growth factor receptor 2 positive; HR-, hormone receptor negative; HR+, hormone receptor positive; PR-, progesterone receptor negative; PR+, progesterone receptor positive; TEACH, Tykerb evaluation after chemotherapy.