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Table 4 Description of loci identified as potential susceptibility sites by ALTree a

From: An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

Site SNP name Position Direction of change Correlated evolution index Major allele Minor allele MAF in pop2
44 MitoT9900C 9,899 T → C 0.390 T C 0.016
57 rs41544217 11,812 G → A 0.324 A G 0.071
72 rs28359178 13,708 G → A 0.318 G A 0.111
  1. aMAF, Mean allele frequency; pop2, BRCA2 mutation carrier.