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Table 1 Univariate and multivariate analyses for pathological complete response

From: The E2F4 prognostic signature is also predictive of the pathological response of breast cancer to chemotherapy

 

Univariate analysis

Multivariate analysis

 

n

Odds ratio (95% CI)

P value

n

Odds ratio (95% CI)

P value

Age, >50 years versus ≤50 years

582

0.79 (0.51 to 1.21)

0.37

   

Histological type

      

 ILC versus IDC

240

2.60 (0.71 to 8.12)

0.19

   

 Other versus IDC

 

1.09 (0.49 to 2.26)

0.85

   

Clinical tumor size, cT2 to cT4 versus cT1

580

0.88 (0.44 to 2.01)

0.79

   

Clinical axillary lymph node status, cN1 to cN3 versus cN0

571

1.37 (0.86 to 2.23)

0.27

   

Grade

      

 2 versus 1

529

1.32 (0.43 to 5.98)

0.72

529

1.22 (0.40 to 5.52)

0.80

 3 versus 1

 

5.56 (1.93 to 24.4)

2.09E-02

 

4.37 (1.48 to 19.4)

0.05

E2F4 metagene-based classification, high risk versus low risk

582

2.40 (1.57 to 3.72)

7.98E-04

529

1.86 (1.14 to 3.08)

4.02E-02

  1. CI, confidence interval; IDC, invasive ductal cancer; ILC, invasive lobular cancer. Bold data indicate significance.