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Table 1 Univariate and multivariate analyses for pathological complete response

From: The E2F4 prognostic signature is also predictive of the pathological response of breast cancer to chemotherapy

  Univariate analysis Multivariate analysis
  n Odds ratio (95% CI) P value n Odds ratio (95% CI) P value
Age, >50 years versus ≤50 years 582 0.79 (0.51 to 1.21) 0.37    
Histological type       
 ILC versus IDC 240 2.60 (0.71 to 8.12) 0.19    
 Other versus IDC   1.09 (0.49 to 2.26) 0.85    
Clinical tumor size, cT2 to cT4 versus cT1 580 0.88 (0.44 to 2.01) 0.79    
Clinical axillary lymph node status, cN1 to cN3 versus cN0 571 1.37 (0.86 to 2.23) 0.27    
Grade       
 2 versus 1 529 1.32 (0.43 to 5.98) 0.72 529 1.22 (0.40 to 5.52) 0.80
 3 versus 1   5.56 (1.93 to 24.4) 2.09E-02   4.37 (1.48 to 19.4) 0.05
E2F4 metagene-based classification, high risk versus low risk 582 2.40 (1.57 to 3.72) 7.98E-04 529 1.86 (1.14 to 3.08) 4.02E-02
  1. CI, confidence interval; IDC, invasive ductal cancer; ILC, invasive lobular cancer. Bold data indicate significance.
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