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Table 2 Correlation between the presence of CTCs and BM-DTCs in BC PDX-bearing mice

From: Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis

  Number of mice with BM-DTCs Number of mice without BM-DTCs
Number of mice with CTCs 16 13
Number of mice without CTCs 2 15
  1. The data are presented in the 2 × 2 collapsed table, ignoring the strata representing different PDX lines. P = 0.0047; Fisher’s Exact test and P = 0.0364; Cochran-Mantel-Haenszel test, adjusting for PDX line.
  2. BC, breast cancer; BM-DTC, disseminated tumor cells in bone marrow; CTC, circulating tumor cell; PDX, patient-derived xenograft.