|
Gene
|
Number of SNPs genotyped
|
Gene-level association P value *
|
|---|
|
AKR1C4
|
1
|
0.44
|
|
AR
|
6
|
0.39
|
|
ARSC
|
2
|
0.02
|
|
COMT
|
21
|
0.14
|
|
CYP11A
|
12
|
0.64
|
|
CYP19A1
|
2
|
0.80
|
|
CYP1A1/CYP1A2
|
5
|
0.97
|
|
CYP1B1
|
15
|
0.61
|
|
CYP21A2
|
2
|
0.13
|
|
CYP2C9
|
16
|
0.73
|
|
CYP3A4
|
3
|
0.46
|
|
ESR1
|
13
|
0.81
|
|
ESR2
|
22
|
0.68
|
|
HSD17B1
|
5
|
0.11
|
|
HSD17B2
|
24
|
>0.99
|
|
HSD17B4
|
24
|
0.49
|
|
HSD17B5/AKR1C3
|
38
|
0.85
|
|
HSD3B1
|
4
|
0.14
|
|
HSD3B2
|
10
|
0.97
|
|
PGR
|
32
|
0.81
|
|
SHBG
|
13
|
0.60
|
|
SLCO1B1 (SLC21A6)
|
38
|
0.04
|
|
SRD5A1
|
24
|
0.80
|
|
SULT1A1/SULT1A2
|
6
|
0.26
|
|
SULT1E1
|
18
|
0.50
|
|
UGT1A8
|
43
|
0.99
|
|
UGT2B17
|
1
|
0.63
|
|
UGT2B7
|
5
|
0.52
|
- *Based on the adaptive rank truncated product (ARTP) statistics. EPT, estrogen and progestin combined therapy; SNP, single nucleotide polymorphisms.
