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Figure 6 | Breast Cancer Research

Figure 6

From: Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays

Figure 6

Schematic diagram of sex-determining region Y (SRY)-box binding protein-2 (Sox2) transcription activity heterogeneity model in breast cancer cells. Our working model depicts that the Sox2 in reporter responsive (RR) cells is distinct from that of reporter unresponsive (RU) cells and confers high transcription activity in that subset perhaps partially through differential interactions with promoter DNA in the nucleus. ChIP, chromatin immunoprecipitation.

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Breast Cancer Research

ISSN: 1465-542X

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