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Figure 1 | Breast Cancer Research

Figure 1

From: Identification by array comparative genomic hybridization of a new amplicon on chromosome 17q highly recurrent in BRCA1 mutated triple negative breast cancer

Figure 1

Comparison of BRCA1 -mutated and non-mutated triple-negative breast cancer (TNBC) array comparative genomic hybridization (CGH) aberration profiles. Frequencies of copy number gains (red) and losses (green) are plotted as a function of genome location for 23 BRCA1-mutated (A) and 21 non-mutated (B) TNBC. The measure of the enrichment of the gains and losses in BRCA1-mutated TNBC in comparison to BRCA1 non-mutated TNBC was calculated with the hypergeometric tail algorithm available in the Agilent software Genomic Workbench 7 (Agilent Technologies). P-values of significant chromosomal regions (P ≤0.1) are plotted according to the genomic position (C).

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