Transducin (β)-like 1 X-linked receptor 1 promotes proliferation and tumorigenicity in human breast cancer via activation of beta-catenin signaling

Table 4 Univariate and multivariate analyses of various prognostic parameters in patients with breast cancer Cox-regression analysis

	Univariate analysis			Multivariate analysis
	Patients, number	P-value	Regression coefficient (SE)	P-value	Relative risk	95% confidence interval
Transducin (β)-like 1 X-linked receptor 1		<0.001	1.642 (0.301)	0.012	2.590	1.237, 5.422
Low expression	103
High expression	111
Ki67		<0.001	1.518 (0.283)	0.034	2.126	1.058, 4.271
Low expression	111
High expression	103
Clinical stage
I	21
II	107	<0.001	0.804 (0.158)	0.007	1.593	1.135, 2.237
III	66	<0.001	0.804 (0.158)	0.007	1.593	1.135, 2.237
IV	20
Pathological differentiation		0.001	0.873 (0.258)	0.026	1.809	1.074, 3.050
Well-differentiated	8
Moderately differentiated	154
Poorly differentiated	52

Transducin (β)-like 1 X-linked receptor 1 (TBLR1) protein expression level in breast cancer significantly correlated with patient survival time (P <0.001). The correlation coefficient was -0.512 indicating that higher levels of TBLR1 expression correlate with shorter survival time. For 5-year survival: low expression, 86.4% (79.1% to 93.7%); high expression, 51.9% (42.1% to 61.7%).

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