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Figure 2 | Breast Cancer Research

Figure 2

From: Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways

Figure 2

Comparison of expression and tyrosine phosphorylation of specific proteins. Immunoblot quantitation of total protein expression compared with relative tyrosine phosphorylation of the corresponding protein, obtained by mass spectrometry (MS). Green represents low phosphotyrosine (pY) peptide abundance as measured by MS, and red indicates high pY peptide abundance. The heat maps indicate the intensity of phosphorylation on the following specific sites: (A) IRS-1 (pY608), (B) p85 (pY467), (C) ErbB3 (pY1325), (D) CDK16 (pY176) and (E) Errfi1 (pY393). Blue bars represent actin-normalised immunoblot intensities for the proteins indicated. PyMT, Polyoma virus middle T antigen.

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Breast Cancer Research

ISSN: 1465-542X

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