Figure 1

Luciferase reporter assays of rs9383935 G/A in MCF-7 and BT-474 cell lines. The G allele constructs had significantly higher luciferase activity than the plasmids bearing the A allele in both the MCF-7 (*P = 0.012) and BT-474 (**P = 0.018) cell lines. Shown are the mean ± SD of relative luciferase expression for plasmids with different alleles after normalized by control groups in parallel experiments.