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Table 2 Immunohistochemical (IHC) scores (0–2) for IGFBP-3 expression in the cytoplasm of invasive ductal cancers and ductal carcinoma in situ

From: Immunohistochemical expression of insulin-like growth factor binding protein-3 in invasive breast cancers and ductal carcinoma in situ: implications for clinicopathology and patient outcome

Cancer type Total no. of tumours IGFBP-3 IHC score
   Negative (0) Weak/moderate (1+) Strong (2+)
Invasive 101 15 54 32
DCIS 102 10 52 40
  1. Tumour numbers scored (0–2) on immunohistochemistry (IHC) for IGFBP-3 expression in the cytoplasm of invasive cancers and ductal carcinoma in situ (DCIS). IHC expression was individually assessed in the nucleus and cytoplasm, and defined as negative (0), weak/moderate (1+) or strong (2+). Positivity for IGFBP-3 expression was defined as an IHC score of (1+/2+).