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Table 1 5-Bromo-2'-deoxyuridine (BrdU) labeling* of MCF10A cells grown in monoculture (control group) and in co-cultures with normal breast-associated fibroblasts (NAF) and carcinoma-associated fibroblasts (CAF)

From: Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture

Culture BrdU-labeling indices of MCF10A cells (mean ± standard error of the mean) BrdU-labeling indices of MCF10A cells (group mean ± standard error of the mean) Comparison of BrdU-labeling indices of MCF10A cells between groups (linear regression)
MCF10A (n = 6) 30.3 ± 3.0 30.3 ± 3.0 MCF10A vs MCF10A + NAF (P = 0.009) MCF10A + NAF vs MCF10A + CAF (P = 0.501)
NAF-1 + MCF10A (n = 7) 21.9 ± 4.2 16.1 ± 2.6 (n = 19)   
NAF-2 + MCF10A (n = 6) 10.7 ± 3.6    
NAF-3 + MCF10A (n = 6) 14.7 ± 5.0    
CAF-1 + MCF10A (n = 8) 15.2 ± 2.0 18.5 ± 2.5 (n = 19) MCF10A vs MCF10A + CAF (P = 0.024)  
CAF-2 + MCF10A (n = 6) 15.5 ± 4.2    
CAF-3 + MCF10A (n = 5) 27.6 ± 6.7    
  1. *Assessed by immunocytochemistry