Table 1 5-Bromo-2'-deoxyuridine (BrdU) labeling* of MCF10A cells grown in monoculture (control group) and in co-cultures with normal breast-associated fibroblasts (NAF) and carcinoma-associated fibroblasts (CAF)
From: Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture
Culture | BrdU-labeling indices of MCF10A cells (mean ± standard error of the mean) | BrdU-labeling indices of MCF10A cells (group mean ± standard error of the mean) | Comparison of BrdU-labeling indices of MCF10A cells between groups (linear regression) | |
|---|---|---|---|---|
MCF10A (n = 6) | 30.3 ± 3.0 | 30.3 ± 3.0 | MCF10A vs MCF10A + NAF (P = 0.009) | MCF10A + NAF vs MCF10A + CAF (P = 0.501) |
NAF-1 + MCF10A (n = 7) | 21.9 ± 4.2 | 16.1 ± 2.6 (n = 19) |  |  |
NAF-2 + MCF10A (n = 6) | 10.7 ± 3.6 |  |  |  |
NAF-3 + MCF10A (n = 6) | 14.7 ± 5.0 |  |  |  |
CAF-1 + MCF10A (n = 8) | 15.2 ± 2.0 | 18.5 ± 2.5 (n = 19) | MCF10A vs MCF10A + CAF (P = 0.024) |  |
CAF-2 + MCF10A (n = 6) | 15.5 ± 4.2 |  |  |  |
CAF-3 + MCF10A (n = 5) | 27.6 ± 6.7 |  |  |  |