Figure 1From: New targets for therapy in breast cancer: Farnesyltransferase inhibitorsRas processing and membrane association: role of farnesy protein transferase (FPTase) and CAAX cleavage. Post-translational modifications of Ras proteins that allow subsequent hydrophobic interaction with the plasma membrane after addition of a 15-carbon farnesyl moiety by the enzyme FPTase. CMT, carboxymethyltransferase; RCE, Ras converting enzyme.Back to article page