Presence of papillomavirus sequences in condylomatous lesions of the mamillae and in invasive carcinoma of the breast

Table 3 Papillomavirus sequences demonstrated

Tumor pairs	Number	HPV types^a
Carcinoma⁺ nipple⁺	17	Same type in both samples: 11 (7×)^b, 6 (1×)^b, 57 (2×) Different types: 3, 15, 16, 20, 21, 23, 27, 37, 38, 66, 87, DL250, DL473, GA3-1
Carcinoma^- nipple⁺	3	6, 11, 32, 37, 66
Carcinoma⁺ nipple^-	8	6, 11, 24, 87, DL250, DL473
Carcinoma^- nipple^-	1

^aInfection with multiple human papillomavirus (HPV) types was demonstrated in eight carcinoma samples (27.6%) and ten nipple samples (34.5%).
^bOne pair harboured HPV 6, HPV 11 and HPV 57 DNA.

ISSN: 1465-542X