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Table 1 50% Inhibitory concentrations for docetaxel in breast cancer cell lines

From: Reduced expression of p27 is a novel mechanism of docetaxel resistance in breast cancer cells

Cell line

IC50 docetaxel (nmol/l)

MCF-7

15

MCF-7 TAX30

10000

MDA-MB-231

40

MDA-MB-231 TAX30

55000

  1. MCF-7 TAX30 and MDA-MB-231 TAX30 are docetaxel-resistant sublines. IC50, 50% inhibitory concentration.