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Table 2 Breast tumor samples and their corresponding immunohistochemistry (IHC), chromogenic in situ hybridization (CISH) results, and tumor histologic grade

From: Chromogenic in situ hybridization (CISH): a novel alternative in screening archival breast cancer tissue samples for HER-2/neu status

IHC score

No. of tests

CISH amplification

Histologic grade

  

Negative

Low

High

1

2

3

0

40

40

0

0

1

33

6

1+

40

40

0

0

3

28

9

2+

40

22

8

10

0

24

16

3+

40

0

9

31

0

27

13

Total

160

102

17

41

4

112

44