From: Oestrogen receptor α gene haplotype and postmenopausal breast cancer risk: a case control study
SNP/haplotype tested | Unadjusted | Adjusted for multiple testing | dfa | |
---|---|---|---|---|
Control v. ductal | Control v. lobular | Control v. ductal | ||
Single loci | ||||
c.454-397C→T | 0.154 | 0.458 | 0.157 | 2 |
c.454-351A→G | 0.128 | 0.292 | 0.235 | 2 |
c.729C→T | 0.524 | 0.440 | -b | 2 |
c.975C→G | 0.037 | 0.845 | 0.106 | 2 |
Two-locus haplotypes | ||||
c.454-397C→T and c.454-351A→G | 0.152 | 0.918 | 0.219 | 3 |
c.454-397C→T and c.975C→G | 0.019 | 0.921 | 0.071 | 3 |
c.454-351A→G and c.975C→G | 0.022 | 0.930 | 0.077 | 3 |
Three-locus haplotype | ||||
c.454-397C→T and c.454-351A→G and c.975C→G | 0.097 | 0.995 | 0.178 | 7 |