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Table 4 Estimated case and control frequencies of predicted ATM haplotypes in the Nurses' Health Study (1989–2000) in comparison with ATM haplotypes in Bonnen and colleagues' study [22]

From: Common ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case–control study

Haplotype Sequencea Previously publishedb Current studyc
       White European American (n = 154) CEPH (n = 70) Controls (n = 3522) Cases (n = 2618) P value
1 A A A C C 0.292 0.394 0.367 0.359 0.51
2 A A G C C 0.013 0.015 0.015 0.014 0.83
3 A C A C C 0.065 0.061 0.048 0.049 0.85
4 T A G A C 0.351 0.273 0.324 0.340 0.22
5 T A G C A 0.175 0.227 0.142 0.130 0.16
6 T A G C C 0.097 0.015 0.096 0.101 0.50
  1. -, the haplotype was not predicted in that population; CEPH (Centre d'Etude du Polymorphisme Humain). a Sequence corresponds to the nucleotide at haplotype tagging single nucleotide polymorphisms 1–5. b From Bonnen and colleagues' study [22]. c Frequencies do not add to 1.0 because rare haplotypes of frequencies less than 0.01 were excluded.