Figure 1

Tumor growth in groups of 10 mice treated with doxorubicin (DOX) followed by the plasmid gene vaccine SINCP-neu (lower line) containing the gene for neu, compared with DOX followed by the negative control plasmid vaccine SINCP-βgal lacking the gene for neu (upper line). The mean tumor volume for mice treated with only DOX (▿) is shown for day 42, and the mean tumor volume for mice treated with only normal saline (▼) is shown for day 36.