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Figure 1 | Breast Cancer Research

Figure 1

From: Malignant myoepithelial cells are associated with the differentiated papillary structure and metastatic ability of a syngeneic murine mammary adenocarcinoma model

Figure 1

Immunocytochemical characterization of LM38-LP, LM38-HP, and LM38-D2 cells (top, middle, and bottom panels respectively). Cell monolayers were stained for the expression of pancytokeratins (pan-CK; left panels) and α-smooth muscle actin (α-SMA; right panels). The LM38-LP cell subline consisted mainly of islets of epithelial cells intensely positive for pan-CK surrounded by α-SMA-positive large myoepithelial cells. The LM38-HP subline predominantly showed small spindle cells positive for pan-CK, which do not form islets, and sparse α-SMA-positive altered myoepithelial cells. The LM38-D2 clone was homogenously made up of α-SMA-stained myoepithelial cells, also positive for pan-CK. (Original magnification ×400; scale bar, 35 μm.)

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Breast Cancer Research

ISSN: 1465-542X

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