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Table 1 Relationship between gene expression pattern and gene function in the 12-point developmental time course

From: Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression

Cluster Transcripts Biological process Molecular function
VSL 357 Metabolism Immunity
   Cell surface signal Signal transducer
   Development  
   ECM and morphogenesis  
G 349 Cell cycle Cell cycle
   Cell growth Cytokine
GSL 605 Biogenesis Cancer
   Cell cycle Enzyme
    Nucleic acid
    Chemokine
LT 35 Cell adhesion Signal transducer
   Metabolism Transport
   Transport Cytokine
   Cell surface signal  
   Intracellular signal  
L 144 Biogenesis Cancer
   Metabolism Transport
   Transport  
   Development  
   ECM and morphogenesis  
LG 83 Cell cycle Enzyme
   Metabolism  
   Development  
   Physiological process  
   ECM and Morphogenesis  
IL 624 Cell death Apoptosis
   Metabolism Immunity
   Transport Signal transducer
   Development Transport
   ECM and morphogenesis  
IT 245 Biogenesis Signal transducer
   Cell cycle  
   Cell growth  
   Cell surface signal  
   Intracellular signal  
IP 156 Biogenesis Immunity
   Homeostasis Signal transducer
   Transport Transport
   Intracellular signal  
IG 582 Cell cycle Cell cycle
   Metabolism Transport
   Proliferation  
   Transport  
PC 93 Transport Transport
   ECM and morphogenesis  
  1. Transcripts representing genes with known function were classified by molecular function and biological process, according to the ontological definitions of the Gene Ontology Consortium. The total numbers of known transcripts classified in this way are shown for each cluster. A statistical test for nonrandom distribution of these functional groups (taking into account the total number of transcripts in each category) was performed on each cluster using Onto-Express. All statistically significant associations (corrected P < 0.05) are listed for each cluster using broad ontological definitions. The genes making up these broad categories are provided on GeNet (see Method section). Additional information on the details of these significant associations and a graphical representation of all ontologies are available as Additional files 1 and 4. ECM, extracellular matrix.