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Figure 2 | Breast Cancer Research

Figure 2

From: Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer

Figure 2

Clustering analysis of levels of mRNA relative to the median. Two distinct clusters of the oestrogen receptor (ER)-positive and ER-negative samples were observed. The mRNA expression of the oestradiol metabolising enzymes, however, did not follow the expression of the ER in all cases, leading to the formation of several subclasses of tumours: grey, ERα+/CYP19-; dark green, ERα+/CYP19+; light green, ERα+/CYP19-/ERβ-; yellow, ERα-/CYP19+/ERβ-; pink, ERα-/CYP19+/ERβ+; blue, ERα-/CYP19-/ERβ-.

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Breast Cancer Research

ISSN: 1465-542X

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