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Table 1 Clinicopathological variables according to c-erbB2 status

From: Cytoplasmic p21WAF1/CIP1 expression is correlated with HER-2/ neu in breast cancer and is an independent predictor of prognosis

  HER-2-negative HER-2-positive P Overall
Total 54 13   67
Oestrogen receptor status     
   ≤ 10 fmol/mg 25 10 0.05* 35
   > 10 fmol/mg 29 3   32
Node status     
   Negative 36 8 0.73 44
   Positive 18 5   23
Histologic grade     
   Grade I 4 0 0.48 4
   Grade II 17 5   22
   Grade III 22 7   29
   'Other' 11 1   12
Nottingham Prognostic Index     
   GPG score ≤ 3.4 4 1 0.61 6
   MPG score 3.4–5.4 28 8   40
   PPG score > 5.4 7 3   10
Age     
   < 50 years 19 8   28
   ≥ 50 years 35 5   39
   Median (range) 56 (32–80) 46 (37–67) 0.03* 55 (32–80)
Tumour size     
   ≤ 2 cm 15 4   19
   > 2 cm 39 9   48
   Median (range) 2.5 (1–5.5) 2.6 (1–5.3) 0.76 2.5 (1–5.5)
  1. GPG, good prognostic group; MPG, moderate prognostic group; PPG, poor prognostic group. *Relationship reached significance (P ≤ 0.05).