Figure 2

Quantitative analysis of osteopontin (OPN) transcripts in human breast tissue components. Epithelial and stromal components were microdissected from tissue sections and subjected to real-time, quantitative PCR analysis. The levels of OPN transcripts were significantly higher (a, b, c, P < 0.05) in all primary breast carcinomas (with and without metastases) than in normal breast epithelia, in fibroadenomas and in associated stromal components. Error bars indicate the standard error of the mean.