Figure 1
From: The contribution of inherited genotype to breast cancer
Role of inherited susceptibility genotypes along the continuum of multistage carcinogenesis to determine exposure (GE), disease risk (GD), efficacy and response to chemoprevention (GP) or treatment (GT), and natural history or disease outcome (GO). B denotes biomarkers of exposure (Bexposure), internal dose (Binternal dose), effective dose (Beffective dose), or early effect (Bearly effect) as defined by Schulte and Perera [12].