Table 1 Cytokines, growth factors and oncogenes that activate signal transducers and activators of transcription (STAT) proteins
STAT1 | STAT3 | STAT5 |
|---|---|---|
IFNα | IL-6, IL-11, OSM, CNTF, LIF | IL-2, IL-7, IL-9, IL-15 |
IFNγ | IL-10 | IL-3, IL-5, GM-CSF |
EGF | Leptin | Growth hormone |
PDGF | EGF | Prolactin |
c/v-Eyk | PDGF | Erythropoetin |
FGF | Insulin | Thrombopoetin |
ACRII | c/v-Src, v-Eyk, v-Abl, v-Fps | EGF |
| Â | c-Fes, Lck, Tel-Jak, Ros, v-Sis | v-Abl |
| Â | Middle T antigen | Â |
STAT2 | STAT4 | STAT6 |
IFNα | IL-12 | IL-4 |
| Â | Â | IL-13 |