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Table 1 Cytokines, growth factors and oncogenes that activate signal transducers and activators of transcription (STAT) proteins

From: Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development

STAT1 STAT3 STAT5
IFNα IL-6, IL-11, OSM, CNTF, LIF IL-2, IL-7, IL-9, IL-15
IFNγ IL-10 IL-3, IL-5, GM-CSF
EGF Leptin Growth hormone
PDGF EGF Prolactin
c/v-Eyk PDGF Erythropoetin
FGF Insulin Thrombopoetin
ACRII c/v-Src, v-Eyk, v-Abl, v-Fps EGF
  c-Fes, Lck, Tel-Jak, Ros, v-Sis v-Abl
  Middle T antigen  
STAT2 STAT4 STAT6
IFNα IL-12 IL-4
   IL-13
  1. IFN, interferon; IL, interleukin, EGF, epidermal growth factor; PDGF, platelet-derived growth factor.