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Table 4 Reclassification of five-year absolute risk of breast cancer based on a risk model containing Gail variables with and without genetic risk scores (GRS) on 411 breast cancer patients and 1,212 healthy women, The Singapore Chinese Health Study, 1993 to 1998

From: Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population

Five-year risk without GRS (%) Five-year risk with GRS (%)
<1.0 1.0 - <1.5 1.5 - <2.0 2.0 - <2.5 ≥2.5 Total
<1.0       
Control 511 84 0 0 0 595
Case 109 46 0 0 0 155
1.0 - <1.5       
Control 90 356 33 0 0 479
Case 36 123 39 0 0 198
1.5 - <2.0       
Control 0 53 50 12 0 115
Case 0 13 19 12 0 44
2.0 - <2.5       
Control 0 0 12 3 1 16
Case 0 0 4 2 3 9
>2.5       
Control 0 0 0 2 5 7
Case 0 0 0 1 4 5
Total       
Control 601 493 94 18 6 1,212
Case 145 182 62 15 7 411