Table 2 Diagnostic performance of five-protein and four-protein classification models
Model | Cancer patients | Healthy volunteers | Sensitivity (%) | Specificity (%) | Overall accuracy (%) | ROC-AUC |
|---|---|---|---|---|---|---|
Five-protein panel | ||||||
Training set | 92* | 46* | 97.6 | 87.1 | 93.1 | 0.961 |
Validation set | 95* | 68* | 86.8 | 92.4 | 89.4 | 0.939 |
Four-protein panel | ||||||
Training set | 92* | 46* | 90.5 | 79.9 | 85.3 | 0.935 |
Validation set | 95* | 68* | 92.6 | 82.4 | 88.6 | 0.954 |