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Table 3 Association of rs10235235 with age at menarche for women of European ancestry by case-control status

From: Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

rs10235235 genotype

Cases

Age at menarche (years)

P trend

Controls

Age at menarche (years)

P trend

AA

22,954

12.83

 

23,383

12.95

 

AG

4,312

12.83

 

4,627

13.02

 

GG

207

12.83

 

248

13.05

 

Total

27,473

12.83

0.97

28,258

12.96

0.005

  1. H0, null hypothesis; Ptrend, test of H0 no linear trend in age at menarche according to rs10235235 genotype.