International study on inter-reader variability for circulating tumor cells in breast cancer

Breast Cancer Research

Table 3 Percent agreement between academic readers and Veridex consensus (VC) overall and according to dataset, disease stage, circulating tumor cell (CTC) count and administration of systemic therapy before blood sample collection

	Agreement, %
	Median	Range	P-value
All	92	69 to 97
Dataset
Institute Jules Bordet	81	61 to 97	<0.001
Institute Curie	97	73 to 99
University of Hamburg	94	69 to 98
Stage
M0	91	70 to 96	<0.001
M1	98	64 to 100
CTC count
<5 CTCs	88	66 to 95	<0.001
≥5 CTCs	97	74 to 100
Systemic therapy before blood sample collection
No	92	74 to 96	<0.001
Yes	89	55 to 97

ISSN: 1465-542X