A methodology to ensure and improve accuracy of Ki67 labelling index estimation by automated digital image analysis in breast cancer tissue

Table 5 Pairwise correlations between the reference values, visual estimates and digital image analysis results (Pearson’s coefficients, P <0.0001, n = 164)

Measurement	Ki67-count	Ki67-DIA-2	Ki67-DIA-1	Ki67-DIA-0	Visual median	Ki67-VE-1	Ki67-VE-2	Ki67-VE-3	Ki67-VE-4
Ki67-DIA-2	0.949
Ki67-DIA-1	0.945	0.989
Ki67-DIA-0	0.928	0.974	0.976
Ki67-VE-median	0.930	0.940	0.946	0.927
Ki67-VE-1	0.861	0.917	0.921	0.925	0.891
Ki67-VE-2	0.905	0.905	0.915	0.886	0.955	0.829
Ki67-VE-3	0.921	0.921	0.931	0.900	0.969	0.857	0.972
Ki67-VE-4	0.887	0.894	0.895	0.884	0.936	0.857	0.881	0.901
Ki67-VE-5	0.842	0.869	0.872	0.860	0.916	0.822	0.853	0.872	0.829

ISSN: 1465-542X