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Table 5 Pairwise correlations between the reference values, visual estimates and digital image analysis results (Pearson’s coefficients, P <0.0001, n = 164)

From: A methodology to ensure and improve accuracy of Ki67 labelling index estimation by automated digital image analysis in breast cancer tissue

Measurement Ki67-count Ki67-DIA-2 Ki67-DIA-1 Ki67-DIA-0 Visual median Ki67-VE-1 Ki67-VE-2 Ki67-VE-3 Ki67-VE-4
Ki67-DIA-2 0.949         
Ki67-DIA-1 0.945 0.989        
Ki67-DIA-0 0.928 0.974 0.976       
Ki67-VE-median 0.930 0.940 0.946 0.927      
Ki67-VE-1 0.861 0.917 0.921 0.925 0.891     
Ki67-VE-2 0.905 0.905 0.915 0.886 0.955 0.829    
Ki67-VE-3 0.921 0.921 0.931 0.900 0.969 0.857 0.972   
Ki67-VE-4 0.887 0.894 0.895 0.884 0.936 0.857 0.881 0.901  
Ki67-VE-5 0.842 0.869 0.872 0.860 0.916 0.822 0.853 0.872 0.829
  1. DIA, digital image analysis; VE, visual estimate.