Skip to main content

Table 2 Summary statistics of the reference values produced by observers, visual estimates and image analyses (n = 30)

From: A methodology to ensure and improve accuracy of Ki67 labelling index estimation by automated digital image analysis in breast cancer tissue

Variable

Median

Mean

Std dev

Std error

Min

Max

Ki67-Count-1

21.7

28.6

20.4

3.7

0.3

72.6

Ki67-Count-2

24

29.9

19.5

3.6

0.6

69.7

Ki67-Count-3

23

28.7

18.6

3.4

1.2

69.4

Ki67-Count-median

24

29.3

19.4

3.5

0.6

67.4

Ki67-Count-mean

23.4

29.1

19.4

3.5

0.7

66.8

Total profiles Observer 1

331

425.7

273.7

50

85

1,098

Total profiles Observer 2

509

590.7

385.4

70.4

143

1,863

Total profiles Observer 3

471.5

547.2

331.9

60.6

146

1,544

Ki67-VE-1

10

18.3

15.3

2.8

5

70

Ki67-VE-2

30

40.2

29.4

5.4

2

95

Ki67-VE-3

37.5

41.4

27.7

5.1

1

90

Ki67-VE-4

20

30.2

23

4.2

4

80

Ki67-VE-5

22.5

31

24.1

4.4

1

90

Ki67-VE-median

22.5

32.5

25

4.6

2

90

Ki67-VE-mean

23.4

32.2

23.2

4.2

6.2

80

Ki67-DIA-0

16.1

19.9

12.5

2.3

2.1

50

Ki67-DIA-1

18.5

24.8

15.9

2.9

1.6

65.5

Ki67-DIA-2

22.8

29.1

15.7

2.9

9.1

68.4