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Figure 1 | Breast Cancer Research

Figure 1

From: A methodology to ensure and improve accuracy of Ki67 labelling index estimation by automated digital image analysis in breast cancer tissue

Figure 1

Test grid of frames from the stereology module overlaid on the TMA spot image. The left and bottom lines of a frame are “forbidden” - nuclear profiles intersecting them are not marked. The short line marks (orange for Ki67-positive, green for Ki67-negative tumour cell nuclear profiles) are produced manually by an observer. Total numbers and Ki67 LI are computed by the software at the end of the procedure. TMA, tissue microarray.

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