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Table 3 Targeted qPCR analysis of mammary glands after 3, 4, or 10 weeks on HFD versus LFD

From: Pubertal high fat diet: effects on mammary cancer development

Inflammation PCR array Fold change HFD versus LFD
Symbol Description 3 wks MG 4 wks MG 10 wks MG
Ccl24 Chemokine (C-C motif) ligand 24 2.7 - -
Ccl3 Chemokine (C-C motif) ligand 3 2.3 - -
Il4 Interleukin 4 2.2 - -
Il5ra Interleukin 5 receptor, alpha 3.0 - -
RANKL Receptor activator of nuclear factor kappa-B ligand - 17 -
Ccl1 Chemokine (C-C motif) ligand 1 - - 4.5
Ccl17 Chemokine (C-C motif) ligand 17 - - 3.2
Ccl19 Chemokine (C-C motif) ligand 19 - - 7.5
Ccl20 Chemokine (C-C motif) ligand 20 - - 5.2
Ccl22 Chemokine (C-C motif) ligand 22 - - 7.6
Il1b Interleukin 1 beta - - 2.1
Il2rb Interleukin 2 receptor, beta chain - - 2.7
Cxcr2 Chemokine (C-X-C motif) receptor 2 - - 4.3
Lta Lymphotoxin A - - 3.2
Xcr1 Chemokine (C motif) receptor 1 - - 2.5
  1. N = 3 high fat diet (HFD) mice, n = 3 low fat diet (LFD) mice; n = 3 mice with early developing tumors while on HFD (HFD-E), n = 3 LFD mice with tumors. P ≤0.05 for all genes listed.