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PB.31: B3 lesions and vacuum-assisted biopsy: a national survey to gauge current practice
Breast Cancer Research volume 15, Article number: P31 (2013)
Breast screening detects asymptomatic abnormalities which occasionally on biopsy are classified indeterminate (B3). Such lesions have malignant potential and traditionally are subject to open diagnostic excision biopsy. Vacuum-assisted biopsy (VAB) offers larger representative tissue sampling, and may act as a therapeutic measure completely excising the lesion. The use of VAB in the NHSBSP varies widely. Currently there are no relevant national guidelines to streamline practice.
A survey was sent to 80 screening units throughout England, comprising seven questions concerning the use of VAB for B3 lesions.
Fifty-four responses (67.5%) were received. Twenty-two per cent of units do not perform VAB, 55% perform first-line and 77.8% second-line VAB. For B3 lesions without atypia, 68% would proceed to second-line VAB whilst 25% advocate open diagnostic excision following initial (14G) core. Management of B3 lesions with atypia was more discordant, with the majority of units opting for second-line VAB for FEA, ALH and LCIS, and second-line diagnostic excision for radial scars, ADH (atypical intraductal proliferation) and papillomas with atypia. Following first-line VAB, most units would proceed to diagnostic excision rather than second-line VAB.
Management of B3 lesions varies significantly across screening units. There is no concordance in the use of VAB for diagnosis or management of B3 lesions. Whilst there is a trend toward second-line VAB for atypias, significant numbers still opt for diagnostic excision. Consensual national guidelines to standardise and guide management would provide equity of care for this difficult management entity.
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Strachan, C., Shaaban, A., Horgan, K. et al. PB.31: B3 lesions and vacuum-assisted biopsy: a national survey to gauge current practice. Breast Cancer Res 15, P31 (2013). https://doi.org/10.1186/bcr3531
- National Survey
- National Guideline
- Malignant Potential
- Excision Biopsy