Volume 15 Supplement 1
PB.16: Contrast-enhanced digital mammography: a single-centre experience
© O'Neill et al.; licensee BioMed Central Ltd. 2013
Published: 8 November 2013
Contrast-enhanced mammography is a relatively novel technique. We describe a single-centre experience with use of the technique to facilitate the detection and characterisation of lesions in the breast by triangulation of contrast-enhanced mammography, biopsy/gross pathological specimen and MR findings.
Retrospective review of the pathological and imaging findings of consecutive patients undergoing contrast mammography was performed. Sixty-four contrast mammograms were performed on 61 patients (all female, mean age 54.3 ± 13.2 years) over a 15-month period. Technique involves a dual energy acquisition of CC and MLO views following the administration of contrast medium, then digital subtraction (GE Senographe DS).
At contrast-enhanced digital mammography, enhancement was observed in 37 of 43 patients with biopsy-proved cancers. Of the six patients with a cancer diagnosis but no enhancement, three were post neoadjuvant treatment. Three patients without a tissue diagnosis of malignancy demonstrated mammographic enhancement. Fourteen patients also underwent gadolinium-enhanced breast MR. Nine out of 10 patients with MR enhancement also demonstrated enhancement on contrast mammogram. One patient with no MRI enhancement had enhancement on contrast mammography. Morphology generally correlated with the pathologic diagnosis.
The results of this study demonstrate the utility of contrast-enhanced mammography in the identification, evaluation and follow-up of breast lesions. It offers similar enhancement characteristics to MRI and represents a feasible alternative in centres without onsite MRI.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.