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Table 1 Comparison of metabolism type, mitochondrial status and autophagy status between the Warburg effect theory and reverse Warburg effect theory a

From: Metabolic interaction between cancer cells and stromal cells according to breast cancer molecular subtype

 

Warburg effect theory

Reverse Warburg effect theory

 

Cancer cell

Cancer cell

Stromal cell

Metabolism

Glycolysis

OXPHOS

Glycolysis

Mitochondrial status

Dysfunctional

Functional

Dysfunctional

Autophagy status

Not included

Not activated

Activated

  1. aOXPHOS, oxidative phosphorylation.