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Table 1 Relationship between levels of Nuc-pYStat5 and other tumor variables in Cohort I

From: Prolactin-Stat5 signaling in breast cancer is potently disrupted by acidosis within the tumor microenvironment

 

Nuc-pYStat5 n(%)

Fisher’s exact test, P

High

Low

GLUT1

High

0 (0)

9 (100)

0.009

Low

20 (46.5)

23 (53.5)

PrlR

High

9 (45)

11 (55)

0.561

Low

11 (34.4)

21 (65.6)

Ki67

> = 15%

11 (35.5)

20 (64.5)

0.770

<15%

9 (42.9)

12 (57.1)

Histology

IDC

18 (39.1)

28 (60.9)

0.784

ILC

2 (50)

4 (50)

ER/PR

Positive

18 (45.0)

22 (55.0)

0.100

Negative

2 (16.7)

10 (83.3)

Total

 

20 (38.5)

39 (61.5)

52

  1. *Positive (ER/PR) status means ER or PR is positive, whereas negative ER/PR status means that the specimen is negative for both receptors. Nuc-pYStat5, nuclear localized and tyrosine phosphorylated Stat5; GLUT1, glucose transporter 1; PrlR, prolactin receptor; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; ER, estrogen receptor; PR, progesterone receptor.