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Table 5 Association between percentage density (≥25% compared with <25%) and local recurrence stratified on surgical method

From: Possible influence of mammographic density on local and locoregional recurrence of breast cancer

 

Breast-conserving surgery

Mastectomy

Local recurrence

41 events

Time at risk = 5,959 years

21 events

Time at risk = 3,734 years

 

HR

CI

P value

HR

CI

P value

Model 1a

1.53

0.70-3.31

0.286

3.44

1.26-9.38

0.016

Model 2b

1.48

0.67-3.25

0.334

2.93

1.03-8.39

0.045

Locoregional recurrence

61 events

Time at risk = 5,924 years

42 events

Time at risk = 3,690 years

 

HR

CI

P value

HR

CI

P value

Model 1a

1.45

0.78-2.70

0.242

2.69

1.34-5.43

0.006

Model 2b

1.57

0.83-2.97

0.166

2.16

1.02-4.54

0.044

  1. aAdjusted for age, body mass index (BMI), and hormone replacement therapy (HRT) use.
  2. bAdjusted for age, BMI, HRT use, mode of detection, tumor size, lymph node metastasis, estrogen receptor status, progesterone receptor status, and grade. CI, confidence interval; HR, hazard ratio.