Skip to main content

Table 2 Medians and inter-decile ranges, estrogen metabolitesa cases and controls, Columbia MO Serum Bank Cohort Breast Cancer Study

From: Relationship of serum estrogens and estrogen metabolites to postmenopausal breast cancer risk: a nested case-control study

  Cases Controls
  Median Inter-decile range Median Inter-decile range
Parent Estrogens 50% 10% 90% 50% 10% 90%
Estrone       
total 252.76 108.7 676.4 226.76 96.5 842.7
conjugated 203.25 75.1 577.6 183.25 68.7 741.1
unconjugated 46.62 25.5 85.5 43.47 22.8 97.5
Estradiol       
total 26.80 11.4 72.0 22.94 10.1 105.7
conjugated 13.73 5.0 40.8 12.06 4.9 45.2
unconjugated 11.19 4.5 36.3 10.02 4.1 41.3
2-Pathway       
2-hydroxyestrone 75.30 64.4 136.5 73.92 64.7 155.0
2-hydroxyestradiol 12.21 12.2 46.3 22.96 12.5 50.3
2-methoxyestrone       
total 43.65 7.4 84.2 41.42 22.3 100.4
conjugated 23.85 7.4 55.0 25.15 9.2 59.4
unconjugated 16.38 6.7 43.5 15.33 5.7 42.5
2-methoxyestradiol       
total 13.53^ 6.4 29.4 15.68 6.9 37.6
   conjugated 9.91^ 3.7 25.7 11.40 4.3 36.0
unconjugated 2.51 1.0 7.9 2.16 0.9 8.0
2-methoxyestrone,3-methyl ether 5.63 1.9 16.9 6.58 2.2 16.5
4-Pathway       
4-hydroxyestrone 19.99 14.1 33.2 17.61 13.4 36.7
4-methoxyestrone 3.48 1.0 7.4 3.60 1.3 7.3
4-methoxyestradiol 1.89 1.0 5.3 1.97 1.0 5.5
16-Pathway       
16α-hydroxyestrone 37.87 27.8 72.9 37.25 27.5 85.0
Estriol       
total 283.29 167.2 580.9 271.98 163.4 624.7
conjugated 245.97 131.8 536.9 227.52 126.4 598.7
unconjugated 32.69 8.1 84.8 26.71 7.8 73.7
16-ketoestradiol 32.05 20.6 64.0 31.59 19.3 76.7
16-epiestriol 5.97 2.3 20.5 5.50 1.9 19.0
17-epiestriol 2.21 1.1 8.1 2.33 1.0 7.5
Total EM 837.91 540.4 1777.9 802.76 512.7 2151.8
  1. apmol/l. ^P <0.05, Wilcoxon rank sum test of differences between cases and controls.
\