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Table 1 Distribution of cases and controls by breast cancer risk factors and matching characteristics; Columbia Missouri Serum Bank Cohort Breast Cancer Case-Control Study

From: Relationship of serum estrogens and estrogen metabolites to postmenopausal breast cancer risk: a nested case-control study

    Cases Controls  
    Number % Number %  
    215 100 215 100  
Breast cancer risk factors      
   Family history of breast cancer      
   yes 67 31.2 55 25.6 P = 0.199
  BMI       
   <25 89 41.4 95 44.2  
   25-29 87 40.5 80 37.2  
   30+ 39 18.1 40 18.6 P = 0.778
   Mean (SD)    26.2 (+/- 3.9)    26.5 (+/- 4.8)  
  Ever smoke      
   yes 58 27.0 56 26.0 P = 0.270
  Age at menarche      
   <12 28 13.0 30 14.0  
   12 58 27.0 49 22.8  
   13 71 33.0 75 34.9  
   14+ 58 27.0 61 28.4 P = 0.799
Reproductive history      
   Never pregnant 36 16.7 34 15.8 P = 0.811
   Number of prenanciesa      
   1-2 102 57.0 83 45.9  
   3-4 57 31.8 66 36.5  
   5+ 20 11.2 32 17.7 P = 0.002
   Age at first pregnancya      
   <20 24 13.4 34 18.8  
   20-24 98 54.7 85 47.0  
   25-29 38 21.2 41 22.7  
   30+ 19 10.6 21 11.6 P = 0.415
   mean (SD)    23.9 (+/- 4.2)    24.2 (+/-4.7)  
aamong parous women      
   Age at menopause      
   <45 40 18.6 38 17.7  
   45 to 49 53 24.7 63 29.3  
   50 to 54 89 41.4 91 42.3  
   55+ 20 9.3 10 4.7  
   unknown 13 6.0 13 6.0 P = 0.371
Years to breast cancer diagnosis (from blood draw)    
   <1 7 3.3    
   1 to <2 10 4.7    
   2 to <3 18 8.4    
   3 to <4 21 9.8    
   4-<5 9 4.1    
   5+ 150 69.8    
Matching factors      
Age at blood collection      
   <55 60 27.9 62 28.8  
   55 to 59 58 27.0 49 22.8  
   60 to 64 45 20.9 43 20.0  
   65 to 69 33 15.3 35 16.3  
   70+ 19 8.8 26 12.1  
Type of menopause      
   Natural 154 71.6 152 70.7  
   Ovariectomy 26 12.1 28 13.0  
   Hysterectomy after age 54 22 10.2 22 10.2  
   Early hysterectomy <age 54 13 6.0 13 6.0  
Years between menopause and blood collection     
   <1 6 2.8 6 2.8  
   1 to <2 15 7.0 17 7.9  
   2 to <3 10 4.7 8 3.7  
   3 to <4 9 4.2 9 4.2  
   4+ 175 81.4 171 79.5  
   unknown    4 1.9  
Time of blood collection      
   11 am to 1 pm 82 38.1 80 37.2  
   2 pm to 5 pm 62 28.8 60 27.9  
   6 pm to 10 pm 71 33.0 71 33.0  
   unknown    4 1.9  
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