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Table 3 DACT1 methylation and clinicopathologic features of breast tumors

From: DACT1, an antagonist to Wnt/β-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer

Clinicopathologic features Number (N= 134) DACT1methylation status Pvalue
   Methylated Unmethylated  
Age (years) ≤40 11 2 9 0.229
  > 40 86 30 56  
  Unknown 37 8 29  
Tumor grade I 7 2 5 0.425
  II 56 21 35  
  III 5 1 4  
  Unknown 66 16 50  
Tumor size ≤2.0 cm 44 14 30 0.21
  ≥2.0 cm, ≤5.0 cm 48 18 30  
  > 5.0 cm 4 0 4  
  unknown 38 8 30  
Lymph node metastasis Positive 43 16 27 0.38
  Negative 41 12 29  
  Unknown 50 12 38  
Distant metastasis Positive 1 1 0 0.114
  Negative 98 32 66  
  Unknown 35 7 28  
ER status Positive 45 17 28 0.274
  Negative 29 9 20  
  Unknown 60 14 46  
PR status Positive 34 11 23 0.296
  Negative 40 15 25  
  Unknown 60 14 46  
HER2 status Positive 42 15 27 0.148
  Negative 28 11 17  
  Unknown 64 14 50  
  1. ER, estrogen receptor; HER2, human epidermal growth factor receptor-2; PR, progesterone receptor.