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Figure 5 | Breast Cancer Research

Figure 5

From: Oestrogen increases the activity of oestrogen receptor negative breast cancer stem cells through paracrine EGFR and Notch signalling

Figure 5

In vivo assessment of oestrogenic effect on breast cancer stem cells. (A) Growth curves for xenografts produced from 1,000 cells pre-treated ± 17β-estradiol, ± inhibitors. *P = 0.01 (B) In vivo tumour formation in each group represented as mice positive for growth/mice tested displayed for each cell number tested. Tumour initiating cell frequency (95% CI) estimates calculated from limiting dilution analysis.

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