- Poster presentation
- Open access
- Published:
Indications for marker clip in the setting of neoadjuvant/neoendocrine therapy
Breast Cancer Research volume 14, Article number: P54 (2012)
Introduction
We are aware that the use of neoadjuvant therapy (NACT) and neoendocrine therapy (NAET) is steadily increasing and more patients are being referred for marker clip placement. This is our experience of the indications for marker clip placement in a large cancer unit using both NACT and NAET for treatment of breast cancers.
Methods
An 18-month retrospective audit was performed to see which patients were having marker clip placement. We recorded the indication for marker clip, final surgery and whether the marker clip was used for localisation.
Results
Fifty patients of the 92 had marker clip placement, of which 37 had NACT and 13 NAET. The marker clip was placed in 35/50 as radiology raised the possibility of near or complete pathological response. In 8/50 the marker clip was placed to aid the pathologist because of concern regarding residual low-volume disease in patients having WLE or mastectomy and 7/50 were trial patients. Thirty-eight patients had WLE and the marker clip was localised in 6/38 cases. Ten patients had mastectomy and in two cases no surgery was performed due to proven metastatic disease. Nine patients had complete pathological response.
Conclusion
Due to NACT and NAET, radiologists and pathologists are facing new challenges in localising and identifying residual low-volume disease following completion of treatment. Marker clip placement can play a crucial role in ensuring accurate localisation at the time of surgery and can aid identification of residual disease for the pathologist.
Author information
Authors and Affiliations
Rights and permissions
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
About this article
Cite this article
Fletcher, M., Dall, B. & Sharma, N. Indications for marker clip in the setting of neoadjuvant/neoendocrine therapy. Breast Cancer Res 14 (Suppl 1), P54 (2012). https://doi.org/10.1186/bcr3309
Published:
DOI: https://doi.org/10.1186/bcr3309