Skip to main content

Imaging features of noncalcified DCIS

Objective

To illustrate the radiological features of noncalcified DCIS (NC-DCIS) on mammography, ultrasound and MRI. To highlight the role of MRI in determining extent of disease.

Introduction

DCIS accounts for 20% screen-detected cancers and 5% of symptomatic cancers. Eighty to 90% present mammographically as microcalcifications, but 10 to 20% are noncalcified and can be mammographically occult. With reported re-excision rates as high as 65% for breast-conserving surgery in DCIS, accurately determining disease extent on preoperative imaging is important.

Methods

Imaging of 117 patients with pure DCIS from 2007 to 2011 was reviewed retrospectively. Fifteen patients with NC-DCIS were identified. Imaging findings were compared with disease extent on postoperative histology.

Results

NC-DCIS appeared as follows. Mammography: occult 33%, diffuse increased breast density 33%, focal architectural distortion 13%, well-circumscribed lesion 13%, tubular ductal density 7%. Ultrasound: occult 7%, intraductal lesion 13%, microcystic lesion 13%, solid lesion 53%, ill-defined echo poor focus 13%. MRI: nonmass-like nodular enhancement in a ductal, segmental or regional distribution 83%, amorphous nonmass-like enhancement 17%. MRI best depicted the true extent of disease.

Conclusion

Recognition of these imaging features is important for accurate surgical planning. MRI has an important role in accurately delineating disease extent and should be considered in treatment planning for NC-DCIS.

References

  1. 1.

    Mesurolle B, et al: Mammographically non-calcified ductal carcinoma in situ: sonographic features with pathological correlation in 35 patients. Clin Radiol. 2009, 64: 628-636. 10.1016/j.crad.2008.12.013.

    CAS  Article  PubMed  Google Scholar 

  2. 2.

    Raza S, et al: Pure ductal carcinoma in situ: a range of MRI features. AJR. 2008, 191: 689-699. 10.2214/AJR.07.3779.

    Article  PubMed  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to JM Scudder.

Rights and permissions

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and Permissions

About this article

Cite this article

Scudder, J., Parikh, J. Imaging features of noncalcified DCIS. Breast Cancer Res 14, P37 (2012). https://doi.org/10.1186/bcr3292

Download citation

Keywords

  • Breast Density
  • Disease Extent
  • Architectural Distortion
  • Symptomatic Cancer
  • Nodular Enhancement