Height, adiposity and body fat distribution and breast density in young women

Breast Cancer Research

Table 5 Percentage and absolute dense breast volume differences with difference in mutually adjusted anthropometric and body composition measures

	Percentage dense breast volume^a				Absolute dense breast volume^a
	% Diff	95% CI	Pvalue	R ^2b	% Diff	95% CI	Pvalue	R ²
Anthropometric measures
BMI (kg/m²)	-29.1	-48.2, -3.1	0.03	0.61	13.4	-19.1, 58.8	0.47	0.29
Waist circumference (cm)	-28.6	-49.4, -0.7	0.06		-22.5	-47.9, 15.2	0.21
DXA measures
Total fat (%)	-26.1	-34.1, -17.3	< 0.001	0.71	-2.4	-16.7, 14.3	0.76	0.30
A:G ratio	-37.2	-40.3, -34.0	< 0.001		-18.5	-27.8, -7.9	0.001

Percentage difference in percentage and absolute dense breast volume with a one-standard-deviation difference in mutually adjusted anthropometric and dual-energy X-ray absorptiometry (DXA) measures. Results also are interpretable as the excess relative ratio. To convert to the relative ratio (RRatio), use the formula: RRatio = (%Diff + 100)/100. A:G, android:gynoid fat ratio; BMI, body mass index; CI, confidence interval. ^aEstimates from two linear mixed-effects models including clinic as a random effect and anthropometric and body composition variables, race, education (attended college), smoking status, duration of hormone use, parity, and BMI z-score at 8 to 10 years old as fixed effects. ^bProportion of variance explained by model.