Skip to main content

Advertisement

Table 3 Percentage dense breast volume differences associated with difference in anthropometric and body composition measures

From: Height, adiposity and body fat distribution and breast density in young women

  Unadjusteda Adjustedb Also adjusted for childhood or young adult BMIc
  % Diff 95% CI Pvalue R 2d % Diff 95% CI Pvalue R 2 % Diff 95% CI Pvalue R 2
Adult anthropometric measures           
   Height (cm) 3.7 -13.8, 24.8 0.70 < 0.01 21.0 9.4, 33.8 < 0.001 0.55 18.7 6.7, 32.1 0.002 0.57
   BMI (kg/m2) -50.2 -55.0, -44.8 < 0.001 0.49 -50.2 -55.4, -44.4 < 0.001 0.54 -45.1 -51.5, -37.8 < 0.001 0.56
   Waist (cm) -51.9 -58.8, -43.8 < 0.001 0.38 -51.5 -59.7, -41.6 < 0.001 0.47 -44.4 -51.0, -37.0 < 0.001 0.56
Adult DXA measures            
   Total fat (%) -50.8 -55.0, -46.4 < 0.001 0.53 -50.1 -55.0, -44.7 < 0.001 0.55 -44.4 -49.6, -38.7 < 0.001 0.60
   A:G ratio -52.3 -55.6, -48.8 < 0.001 0.57 -52.0 -54.5, -49.5 < 0.001 0.60 -47.0 -48.5, -45.4 < 0.001 0.67
Childhood BMI             
   BMI z-score at 8 to 10 years old -40.0 -47.0, -32.0 < 0.001 0.22 -41.7 -47.5, -35.2 < 0.001 0.34 -17.3 -22.4, -11.9 < 0.001 0.56
  1. Percentage differences (%Diff) in percentage dense breast volume associated with a one-standard-deviation difference in anthropometric and dual-energy X-ray absorptiometry (DXA) body composition measures. Results are also interpretable as the excess relative ratio. To convert to the relative ratio (RRatio), use the formula: RRatio = (%Diff + 100)/100. A:G ratio, android:gynoid fat ratio; BMI, body mass index; CI, confidence interval. aEstimates from six linear mixed-effects models including clinic as a random effect and anthropometric and body composition variables as fixed effects. Anthropometric and body composition variables are modeled separately without mutual adjustment. bEstimates from six linear mixed-effects models as described for unadjusted plus including race, education (attended college), smoking status, duration of hormone use, and parity as fixed effects. Model for height also includes weight as a fixed effect. cEstimates from six linear mixed-effects models as described for adjusted plus including BMI z-score at 8 to 10 years old as a fixed effect in adult anthropometric and DXA models and young adult BMI in the childhood BMI model. dProportion of variance explained by model.