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Figure 1 | Breast Cancer Research

Figure 1

From: Promoter hypermethylation in male breast cancer: analysis by multiplex ligation-dependent probe amplification

Figure 1

Hierarchical clustering analysis of male breast cancer patients. Unsupervised hierarchical clustering of absolute methylation percentages in 25 genes in 108 male breast cancer patients. One gene cluster consisted of WT1, CDH13, MSH6, PAX5, GSTP1, GATA5 and PAX6, seven genes in which methylation was very common. The second cluster was formed by genes with intermediate methylation rates (5 to 19%), and in the third cluster the remaining genes with little methylation (< 8%) grouped together. No clear distinctive clusters of male breast cancer cases were found.

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