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Table 4 Per-lesion sensitivity to malignant lesions and false-positive marks per case using BI-RADS score of at least 4 to define a positive mark

From: Dual-energy contrast-enhanced digital mammography: initial clinical results of a multireader, multicase study

Reader MX ± US MX ± US ± CEDM Difference Pvalue
Sensitivity
1 0.702 ± 0.050 0.762 ± 0.047 0.060 0.13
2 0.738 ± 0.048 0.81 ± 0.043 0.071 0.08
3 0.738 ± 0.048 0.845 ± 0.040 0.107 0.01
4 0.762 ± 0.047 0.821 ± 0.042 0.060 0.07
5 0.702 ± 0.05 0.738 ± 0.048 0.036 0.50
6 0.631 ± 0.053 0.690 ± 0.051 0.060 0.18
Overall 0.712 ± 0.043 0.778 ± 0.040 0.065 ± 0.024 0.006
95% CI 0.628 to 0.797 0.697 to 0.858 0.019 to 0.112  
False-positive marks per case (cases without malignant lesions)
1 0.478 ± 0.056 0.652 ± 0.064 0.174 0.034
2 0.565 ± 0.056 0.435 ± 0.052 -0.130 0.128
3 0.652 ± 0.058 0.674 ± 0.067 0.022 0.745
4 1.043 ± 0.06 0.978 ± 0.065 -0.065 0.545
5 0.717 ± 0.052 0.609 ± 0.051 -0.108 0.134
6 0.478 ± 0.056 0.478 ± 0.063 0.000 1.000
Overall 0.656 ± 0.092 0.638 ± 0.089 -0.018 ± 0.050 0.726
95% CI 0.443 to 0.869 0.434 to 0.842 -0.135 to 0.099  
  1. BI-RADS, Breast Imaging, Reporting and Data System; CEDM, contrast-enhanced digital mammography; CI, confidence interval; MX, mammography; US, ultrasonography.
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